The story of the Sackler Dynasty, Purdue Pharma, and their involvement in the opioid crisis that has created millions of addicts, even as it generated billions of dollars in profit. The highly anticipated portrait of three generations of the Sackler family, by the prize-winning, bestselling author of Say Nothing. The Sackler name adorns the walls of many storied institutions – Harvard; the Metropolitan Museum of Art; Oxford; the Louvre. They are one of the richest families in the world, known for their lavish donations in the arts and the sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing Oxycontin, a blockbuster painkiller that was a catalyst for the opioid crisis – an international epidemic of drug addiction which has killed nearly half a million people. In this masterpiece of narrative reporting and writing, Patrick Radden Keefe exhaustively documents the jaw-dropping and ferociously compelling reality. Empire of Pain is the story of a dynasty: a parable of twenty-first-century greed.